Bradley Woolf
Bradley Woolf
Bradley Woolf

Bradley Woolf

‣
Hidden

Bradley Woolf

Programmer

Computational biology, programming, design Merging computers, software, and engineering principles to program biology

X
GitHub
LinkedIn
Discord
Email
Telegram

Want to build something? Book a call

Cal.com 30 Min Meeting | Bradley Woolf | Cal.comCal.com 30 Min Meeting | Bradley Woolf | Cal.com

Projects

Calculating my Polygenic Risk Scores from the Nucleus Origin Model
Sampling energy-based models with Extropic’s thrml
GPU-based whole genome analysis
Building a VAE cell-type annotator
CPU-based whole-genome analysis
Fine-tuning Evo2 to generate novel phage designs
Fine-tuning toolkit for ESM2
Gene therapy pipeline (in silico)
Frances: optimizing E. Coli gene edits → output yields
K-mer counting CUDA kernel
scRNA-seq Leukemia cell pipeline with DL
Ranking proteins with reinforcement learning
Automated variant interpretation (FASTQ → Clinic)
cfDNA fragmentomics with Python
Automated scraping from UniProt, PubMed, Reactome, and KEGG
Bioinformatics code challenges with Python
A soil microbiome pipeline with Nextflow, Kraken2, and MultiQC
De novo antivenom binders with BindCraft, Rosetta, and ProteinMPNN

Writings

Technological progress
Cost structures
Genes from the sci-fi book Upgrade
How each programming language thinks
Shaping a neural network like marble
Regulations for biotech agents
The core primitives all computer programs are built on
Who can I raise money from for my biotech startup?
How do I leverage LLMs to program better?
Cost modeling DL vs linear regression paper
Using AI game engines to simulate synthetic biology
Can deep learning solve bottlenecks in gene therapy?
BioRAG
Gene therapy: can we perceive the body as an RL agent’s environment?
GPU programming and custom kernels
Core crypto algorithms
Core genomic algorithms
The Quantification of biology
The technical bottlenecks that high frequency trading overcame
Making illiquid data liquid
A brief history of quantifying biology
Filtering nature through the dominant technology of the day
Commoditizing health
History of Technology
History of Health
High Level Global Statistics
Scientific Databases

Woolf Software, Inc © 2025